年轻的法克斯坦博士神推鬼撞下来到祖父的城堡，无意中发现了一本祖父的记事簿，在驼背人伊哥与性感野性的伊加帮助下，加上偷回来的脑，根据祖父的科学实验资料，成功制造了一具怪物–科学怪人。可惜，偷回来的脑出了岔子，导致科学怪人极渴望被爱，它离家出走，在郊外遇上小女孩与一名瞎子…… 影史上数一数二爆笑到极点的电影！请务必先看过1931年的《科学怪人》及1935年的《科学怪人的新娘》电影版本再来看本片，因为本片所有镜头、对白、桥段、造型等，皆和旧版作了对比，却大大颠覆成搞笑版本！
无忌（关礼杰饰）与父（叶荣祖饰）以做黄色招牌为生，偶然之下，被一名伴唱少女Katie（容儿饰）误以为是警察。Katie因朋友 而被毒枭Bob（周比利饰）迫其以身偿债，Katie遂以无忌及其警察挚友钊（霍瑞华饰）为挡箭牌，与Bob屡起冲突，Bob一怒之下杀无忌 父及拐走Katie将其轮奸。无忌不想连累朋友，将钊打晕并夺其配枪，准备与 Bob决一死战……
George Bryan Brummel, a British military officer, loves Lady Margery, the betrothed of Lord Alvanley. Despite her own desperate love for Brummel, she submits to family pressure and marries Lord Alvanley. Brummel, broken-hearted, embarks upon a life of revelry. He befriends the Prince of Wales and leaves the army, becoming subsequently the best-known rake and decider of fashion in Europe. As his affairs flourish, so does his disdain for his benefactor, the Prince. Eventually Brummel falls into disfavor, and it is only Lady Margery who has any chance of helping him.
影片改编自余华同名先锋代表作，看似是马哲（朱一龙 饰）在找寻凶案的真相，但故事没有答案，因为命运的看法比我们更准确…… 该片入围第76届戛纳电影节“一种关注”官方单元。
